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Staph Infection

Causes, Symptoms, Diagnosis, Treatment, and Prevention

Staph infections, also known as Staphylococcus infections, encompass a group of bacterial infections caused by the Staphylococcus bacteria. Staphylococcus is a genus of bacteria commonly found on the skin and in the nasal passages of healthy individuals. Although most Staphylococcus bacteria are harmless, some strains can lead to infections that vary from mild skin conditions to severe, potentially life-threatening systemic illnesses. In this informative resource provided by TGH Urgent Care powered by Fast Track, we will cover all aspects of Staph infections, including their causes, symptoms, diagnosis, treatment, and prevention.

Types of Staph Infections

Staphylococcus bacteria can cause various types of infections. The most common ones include:

Staphylococcal Skin Infections

  • Boils: Painful, pus-filled lumps on the skin.
  • Impetigo: A highly contagious skin infection characterized by red sores that rupture, ooze, and then develop yellowish-brown crusts.
  • Cellulitis: An infection that affects the deeper layers of the skin, causing redness, swelling, and tenderness.
  • Staphylococcal scalded skin syndrome (SSSS): A blistering skin condition that occurs mainly in infants and young children.
  • Folliculitis: Inflammation of hair follicles that may cause pimple-like bumps and itching.

Invasive Staph Infections

  • Staphylococcal pneumonia: Infection of the lungs, which can be severe and life-threatening.
  • Osteomyelitis: An infection of the bone.
  • Endocarditis: Infection of the heart valves or inner lining of the heart.
  • Septicemia: A bloodstream infection that can lead to sepsis, a severe and potentially fatal condition.

Toxin-Related Staph Infections

  • Toxic shock syndrome (TSS): A rare but potentially deadly condition linked to the release of toxins by Staphylococcus bacteria.
  • Food poisoning: Consuming food contaminated with Staphylococcus toxins can cause rapid onset of vomiting, diarrhea, and abdominal pain.

Causes and Risk Factors

Staph infections are primarily caused by Staphylococcus bacteria, with Staphylococcus aureus being the most common culprit. These bacteria can enter the body through cuts, wounds, or areas of broken skin. Some of the key risk factors for developing Staph infections include:

Weakened Immune System:

Individuals with weakened immune systems, such as those with HIV/AIDS, cancer, or chronic illnesses, are more susceptible to Staph infections.

Skin Conditions:

Skin conditions that cause breaks in the skin, like eczema or psoriasis, can create entry points for Staph bacteria.

Surgical Procedures:

Invasive medical procedures, surgeries, or the use of medical devices like catheters and implants can introduce Staph bacteria into the body.

Close Contact:

Staph bacteria can spread through close skin-to-skin contact with infected individuals or by sharing contaminated personal items, like towels or razors.

Crowded and Unsanitary Environments:

Living or working in crowded and unsanitary conditions can increase the risk of Staph infection, particularly for food handlers and healthcare workers.

IV Drug Use:

People who inject drugs using contaminated needles are at higher risk of developing Staph infections, including potentially life-threatening bloodstream infections.

Symptoms of Staph Infections

The symptoms of a Staph infection can vary depending on the type and location of the infection. Common symptoms of Staph infections may include:

Skin Infections:

  • Redness and warmth around the affected area.
  • Swelling and tenderness.
  • Pain or discomfort.
  • Pus-filled sores or blisters.
  • Itching or burning sensations.

Invasive Infections:

  • High fever and chills.
  • Fatigue and weakness.
  • Rapid breathing.
  • Nausea and vomiting.
  • Confusion or altered mental state.

Toxin-Related Infections:

  • Sudden high fever.
  • Muscle aches and pains.
  • Headache.
  • Rash resembling sunburn.
  • Rapid drop in blood pressure (in severe cases).

It’s important to seek medical attention if you suspect a Staph infection, especially if you have severe symptoms or underlying health conditions that increase your risk of complications.


Diagnosing a Staph infection typically involves a combination of clinical evaluation and laboratory tests. The following steps are commonly taken to diagnose Staph infections:

Clinical Evaluation:

A healthcare provider will assess your symptoms, medical history, and risk factors. They will also examine any visible skin lesions or wounds.


To confirm the presence of Staphylococcus bacteria and determine their susceptibility to antibiotics, a sample of tissue, pus, blood, or other bodily fluids may be collected and sent to a laboratory for culture.

Blood Tests:

In cases of systemic Staph infections, blood tests may be conducted to check for signs of infection, such as elevated white blood cell counts.


 Imaging tests like X-rays, CT scans, or MRI scans may be ordered to assess the extent of infection in cases of invasive infections like osteomyelitis or endocarditis.


The choice of treatment for a Staph infection depends on the type and severity of the infection, as well as the individual’s overall health. Common approaches to treating Staph infections include:


The majority of Staph infections are managed using antibiotics. The selection of antibiotics is contingent upon the specific type of bacteria involved and their susceptibility to these medications. Your healthcare provider will determine the most suitable antibiotic for your particular case.

Commonly used antibiotics include:

  • Methicillin-resistant Staphylococcus aureus (MRSA), a strain resistant to many antibiotics, may require specialized antibiotics like vancomycin or daptomycin.


To treat skin infections like boils or abscesses, drainage of the pus is often necessary to promote healing. A healthcare provider may do this through incision and drainage (I&D).


In cases of invasive Staph infections involving bone or heart valves, surgical intervention may be required to remove infected tissue or repair damaged structures.

Supportive Care:

Patients with severe Staph infections, particularly those leading to septic shock, may require intensive care with supportive measures such as fluids, oxygen, and medications to stabilize blood pressure.

Wound Care:

Proper wound care is essential for preventing the spread of infection. Keeping the affected area clean and covered can aid in the healing process.

It’s crucial to complete the full course of antibiotics as prescribed by your healthcare provider, even if you start feeling better before the medication is finished. Stopping antibiotics prematurely can lead to antibiotic resistance and a recurrence of the infection.


Preventing Staph infections involves a combination of personal hygiene, infection control measures, and prudent antibiotic use. Here are some key strategies for preventing Staph infections:

Hand Hygiene:

Regularly washing your hands with soap and water for at least 20 seconds can help prevent the spread of Staph bacteria. Alcohol-based hand sanitizers can also be effective when soap and water are not available.

Skin Care:

Keep your skin clean and dry. Promptly clean and cover any cuts or wounds to prevent Staph bacteria from entering the body.

Avoid Sharing Personal Items:

Refrain from sharing personal items like towels, razors, and clothing, as these can harbor and transmit Staph bacteria.

Proper Food Handling:

Food handlers should adhere to strict hygiene and food safety practices to prevent Staph-related food poisoning.

Healthcare Settings:

Healthcare facilities should implement infection control measures, including proper hand hygiene, sterile techniques, and antibiotic stewardship programs to reduce the risk of healthcare-associated Staph infections.


While there is no vaccine specifically for Staph infections, certain vaccines, like the pneumococcal vaccine, can reduce the risk of secondary bacterial infections.

Good Antibiotic Practices:

Antibiotics should only be used when prescribed by a healthcare provider for a confirmed bacterial infection. Overuse or misuse of antibiotics can contribute to antibiotic resistance.

Methicillin-Resistant Staphylococcus aureus (MRSA)

Methicillin-resistant Staphylococcus aureus (MRSA) is a strain of Staphylococcus aureus that has developed resistance to many commonly used antibiotics, including methicillin, penicillin, and amoxicillin. MRSA infections can be particularly challenging to treat as they are less responsive to standard antibiotics.

MRSA can cause a wide range of infections, from skin and soft tissue infections to severe bloodstream infections. It is commonly associated with healthcare settings (healthcare-associated MRSA or HA-MRSA) but can also be community-acquired (community-associated MRSA or CA-MRSA).

Preventing MRSA infections requires enhanced infection control measures, including strict hand hygiene, isolation precautions, and antibiotic stewardship programs in healthcare settings. Treatment of MRSA infections typically involves specialized antibiotics like vancomycin, daptomycin, or linezolid.


Staph infections, caused by Staphylococcus bacteria, can range from mild skin conditions to life-threatening systemic illnesses. These infections can affect individuals with weakened immune systems, those with skin conditions, and people in healthcare settings. Timely diagnosis and appropriate treatment with antibiotics are essential to manage Staph infections effectively.

Prevention measures, including good hand hygiene, proper wound care, and responsible antibiotic use, play a critical role in reducing the incidence of Staph infections.

If you believe you may have a Staph infection or are vulnerable due to pre-existing health issues, it is crucial to promptly seek medical assistance for a proper diagnosis and treatment. You should visit your nearest walk-in clinic and consult with a healthcare professional at TGH Urgent Care. In general, raising awareness, educating individuals, and maintaining rigorous hygiene practices are fundamental in reducing the adverse effects of Staph infections on the overall public health.


Most Staph infections are treated with antibiotics, with the choice of antibiotics depending on the type and antibiotic susceptibility of the bacteria. Your healthcare provider will decide which one suits your needs (CDC, 2021; Mayo Clinic, 2021).

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